Molecular basis of breast cáncer

Authors

  • Marcia Alexandra Silva Mata
  • Lida Estefanía Guillén Miranda
  • Alex Gabriel Lara Jácome

Abstract

Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant breast cancer, accounting for 70–80% of all invasive breast malignancies. IDC demonstrates great heterogeneity in clinical and histopathological features, prognoses, treatment strategies, gene expressions, and proteomic profiles.

Current genomics has been subsumed into diagnostic medicine as clinical genomics, which provides important insights into the genomic drivers of cancer development and progression. Importantly, genomics can even be applied to breast cancer treatment, starting with the identification of mutations in a panel of candidate genes, but focusing on the individual molecular complexity and intraheterogeneity of breast tumors.

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Published

2025-09-05

How to Cite

1.
Silva Mata MA, Guillén Miranda LE, Lara Jácome AG. Molecular basis of breast cáncer. Rev Cubana Inv Bioméd [Internet]. 2025 Sep. 5 [cited 2026 Mar. 4];44. Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/3950