Calcitonin as a preventive agent of root resorption

Authors

  • Cristina Alexandra Clavijo Silva
  • Alba Narcisa Macas Macas
  • Karla Andrea Camacho Medina
  • Luis Fernando Pérez Solís

Keywords:

Root resorption, Calcitonin, orthodontic treatment, periodontal disease, PRISMA 2020

Abstract

Background: Calcitonin is a peptide hormone produced by the parafollicular cells of the thyroid gland and has a hypocalcemic effect by decreasing calcium release from bone.
Objectives: The aim of the study was to analize Calcitonin as a preventive agent of root resorption by systematic review PRISMA 2020.
Methods: This research was a systematic review conducted by means of the PRISMA 2020 methodology. A total of ninety-five articles were reviewed, broken down into forty-four in the SCOPUS database and fifty-one in the PubMed database, after specifying the inclusion and exclusion criteria.
Results: It was shown that Calcitonin is a polypeptide hormone produced by the parafollicular cells of the thyroid gland that has the capacity to decrease osteoclastic activity and, therefore, its use in the treatment of root resorption has been proposed. It was found that Calcitonin may have a preventive effect on root resorption during orthodontic treatment and periodontal disease. However, further research is needed to determine the efficacy and safety of this treatment at various stages of the disease and in diverse types of root lesions.
Conclusions: The reviewed studies highlighted the importance of proper prevention, evaluation, and management of root resorption, as well as the need for further research to improve detection and treatment of this problem.

Downloads

Download data is not yet available.

Published

2023-07-02

How to Cite

1.
Clavijo Silva CA, Macas Macas AN, Camacho Medina KA, Pérez Solís LF. Calcitonin as a preventive agent of root resorption. Rev Cubana Inv Bioméd [Internet]. 2023 Jul. 2 [cited 2025 Aug. 2];42(2). Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/2895