El plasma de convalecientes como un tratamiento potencial en pacientes con COVID-19

Autores/as

Palabras clave:

SARS-CoV-2, COVID-19, inmunoterapia pasiva, plasma de convalecientes, plasma hiperinmune

Resumen

Introducción: El plasma de convalecientes es una inmunoterapia pasiva que se ha usado para el tratamiento y prevención de muchas enfermedades infecciosas por más de un siglo. Dada la falta de tratamiento específico para el nuevo coronavirus SARS-CoV-2, el plasma de convalecientes es una alternativa terapéutica potencial contra la COVID-19.

Objetivo: Realizar una revisión del empleo del plasma de convalecientes como alternativa terapéutica a la COVID-19.

Desarrollo: Se empleó la estrategia de búsqueda del tema; consultando las bases de datos Pubmed, SciELO, Lilacs, Cochrane Library y Web of Science. El plasma de convalecientes ha mostrado efectividad en el tratamiento de varias enfermedades virales. Así, la evidencia sobre su uso en los pacientes con COVID-19 es escasa, aunque se han obtenido resultados alentadores, pero no concluyentes por falta de un número mayor ensayos clínicos. Al mismo tiempo, Cuba incluye en sus protocolos de actuación contra la COVID-19 este tratamiento.

Conclusiones: Esta alternativa resulta una herramienta inmunoterapéutica en los pacientes con la COVID-19, ya que mejora el estado clínico y disminuir la tasa de letalidad. Sin embargo, se necesitan más ensayos clínicos controlados y aleatorizados que afirmen su efectividad y seguridad.

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Citas

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Publicado

2021-02-09

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1.
Rodríguez-Venegas E de la C, Fontaine-Ortiz JE, Ávila-Cabreja JA. El plasma de convalecientes como un tratamiento potencial en pacientes con COVID-19. Rev Cubana Inv Bioméd [Internet]. 9 de febrero de 2021 [citado 2 de agosto de 2025];40(1). Disponible en: https://revibiomedica.sld.cu/index.php/ibi/article/view/893

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