Cognitive evoked potentials P300 and CNV in patients' with Parkinson disease

Autores/as

  • Iván Delgado Suárez General Hospital "Dr. Juan Bruno Zayas Alfonso"
  • Arquímedes Montoya Pedrón General Hospital "Dr. Juan Bruno Zayas Alfonso"
  • Lianne Alicia Chang Arraño University of Medical Sciences Santiago de Cuba

Palabras clave:

cognitive evoked potentials, CNV, P300, Parkinson's disease

Resumen

Introduction: The use of cognitive evoked potentials is useful in many neurological disorders.
Material and methods: A descriptive and traverse study was performed in patients with Parkinson's disease of the Neurology and Neurophysiology department of the Santiago General Hospital "Dr. Juan Bruno Zayas" from Santiago de Cuba, during the period from March 2017 to May 2018. The cognitive evoked potentials (P300-CNV) and a clinical neuropsychological evaluation were carried out. Objective: To identify the relationship possible between cognitive evoked potentials and clinical-neuropsychological variables as diagnostic of the cognitive alterations that occur in patients. Results: a significant prolongation of the latency, with a decrease in the amplitudes of the P300 and CNV with modifications in the morphology of the potential when the clinical neuropsychological evaluations were altered. These suggest that exist a delay in the cognitive processing of information, a decrease in the intensity of selective attention processes and hypofunction in cortical activation with asynchrony in the neurogenerators, in patients with Parkinson's disease, when the clinical and cognitive evaluations are altered. Conclusions: the cognitive evoked potentials are useful, and complement the clinical and neuropsychological evaluation.

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Publicado

2020-01-28

Cómo citar

1.
Delgado Suárez I, Montoya Pedrón A, Chang Arraño LA. Cognitive evoked potentials P300 and CNV in patients’ with Parkinson disease. Rev Cubana Inv Bioméd [Internet]. 28 de enero de 2020 [citado 30 de julio de 2025];38(5). Disponible en: https://revibiomedica.sld.cu/index.php/ibi/article/view/442