The effects of microgravity exposure on maximal oxygen consumption in humans

Authors

Keywords:

microgravity, exercise, cardiovascular oxygen transport, muscle atrophy, models.

Abstract

After a short summary of the multifactorial models of maximal O2 consumption (VO2max) limitation, microgravity exposure is discussed as a convenient experimental condition to test these models. The following points are highlighted: 1) The decrease of (VO2max) in microgravity concerns specifically exercise performed in upright posture upon resumption of gravity exposure; 2) The decrease of (VO2max) after microgravity exposure has two components: one is fast and is related to cardiovascular adaptation, the other is slow and is related to the development of muscle atrophy; 3) (VO2max) does not decrease during microgravity or in supine posture upon resumption of gravity exposure, if the time in microgravity is sufficiently short; 4) cardiovascular oxygen transport accounts for 70% of (VO2max) limitation also after microgravity exposure.

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Author Biography

Guido Ferretti, Université de Genève

Department of Anesthesiology, Pharmacology and Intensive Care, University of Geneva, Switzerland, and Department of Molecular and Translational Medicine, University of Brescia, Italy

Published

2019-09-18

How to Cite

1.
Ferretti G. The effects of microgravity exposure on maximal oxygen consumption in humans. Rev Cubana Inv Bioméd [Internet]. 2019 Sep. 18 [cited 2025 Aug. 1];38(3). Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/271

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Section

SHORT COMMUNICATIONS