Recent perspectives of the automated morphological analysis of erythrocytes

Authors

Keywords:

morphological analysis of erythrocytes, systematic review, automated morphological analysis, sickle-cell anemia.

Abstract

Introduction: Sickle-cell anemia is a genetic hereditary anomaly of hemoglobin characterized by red blood cells that lose their normal round morphology and acquire a sickle shape. Although no cure is so far available, several actions are in progress to improve the quality of life and medical care of patients.

Objective: Become acquainted with aspects related to the automated morphological analysis of erythrocytes in recent years, particularly in the context of sickle-cell anemia, allowing to determine the current limitations, mainly in the use of automated tools for the clinical follow-up of sickle-cell anemia patients.

Methods: A systematic review was conducted of the literature published in the years 2018, 2019, and two contributions from 2020, in three broad scope electronic databases: IEEEXplore, Google Scholar and SCOPUS. The documents were analyzed on the basis of specific questions to obtain general criteria about the situation of interest.

Conclusions: The analysis conducted revealed a growing volume of research in this field, with results in several countries. Detailed examination of the studies led to identification of problems related to the evaluation metrics used, the algorithms for the analysis and processing of images, the use of medical criteria, the databases used and tools for the automated morphological analysis of erythrocytes.

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Author Biographies

Yaima Paz Soto, Universidad de Guantánamo

Profesora Auxiliar del Departamento de Informática. Facultad de Ingeniería y Ciencias Técnicas. Universidad de Guantánamo. Coordinadora de Proyecto Institucional "Procesamiento Digital de Imágenes para el apoyo al monitoreo clínico de pacientes con la enfermedad de las células falciformes"

Silena Herold García, Universidad de Oriente

Profesora Titular y Jefa del Departamento de Ciencias de la Computación de la Universidad de Oriente, coordinadora de varios proyectos de investigación en procesamiento de imágenes médicas.

Published

2021-05-28

How to Cite

1.
Paz Soto Y, Herold García S. Recent perspectives of the automated morphological analysis of erythrocytes. Rev Cubana Inv Bioméd [Internet]. 2021 May 28 [cited 2025 Jul. 27];40(5). Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/878