Hiv-tuberculosis coinfection in a public health unit of santo domingo, Ecuador

Authors

  • Guido Nino Guida Acevedo
  • Rafael Martín Franco Delgado
  • Roberto Javier Aguilar Berrezueta

Keywords:

Tuberculosis, HIV, coinfection, comorbidities, Public Health

Abstract

HIV and tuberculosis coinfection constitutes a significant challenge for global public health, especially in regions with a high prevalence of both diseases. The objective of the study was to describe the clinical behavior of HIV-Tuberculosis coinfection in the internal medicine unit of the “Dr. Gustavo Domínguez” Hospital in the city of Santo Domingo de los Tsáchilas, Ecuador, during the period from January to December 2022. A mixed study based on a series of documented cases was conducted, analyzing demographic, clinical, and diagnostic data from 16 patients. The diagnostic methods used included BK1, GenExpert, and LAN. The results indicated a higher prevalence of coinfection in men (69 %), with a high incidence of extrapulmonary tuberculosis (67 %). The most common comorbidities were syphilis, COVID-19, histoplasmosis, and acute renal failure. Mortality was 6.2 %, with one death in the series of cases. The average age of the patients was 34 years, highlighting a greater impact on the economically active population. The conclusions underscore the need to improve adherence to antiretroviral treatment and diagnostic strategies, as well as to address associated comorbidities and the socioeconomic impact on this vulnerable population. This study highlights the importance of comprehensive and multidisciplinary care for the effective management of HIV-Tuberculosis coinfection.

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Published

2024-12-05

How to Cite

1.
Guida Acevedo GN, Franco Delgado RM, Aguilar Berrezueta RJ. Hiv-tuberculosis coinfection in a public health unit of santo domingo, Ecuador. Rev Cubana Inv Bioméd [Internet]. 2024 Dec. 5 [cited 2025 Dec. 7];43. Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/3600