Papillary thyroid carcinoma

Authors

  • Marcia Alexandra Silva Mata
  • Lida Estefanía Guillén Miranda
  • Alex Gabriel Lara Jácome

Keywords:

Papillary thyroid carcinoma, early diagnosis, thyroidectomy, lymphatic metastasis, narrative review

Abstract

Papillary thyroid carcinoma is the most common type of well-differentiated thyroid cancer, characterized by a generally favorable prognosis, although with variations in presentation and clinical management. This study aimed to synthesize recent literature on papillary thyroid carcinoma, focusing on risk factors and management strategies to improve patient prognosis. A comprehensive search was conducted in PubMed for articles published between 2018 and 2024, resulting in 2,885 documents, of which 14 relevant ones were selected for analysis. The results highlighted the importance of factors such as sex, age, tumor diameter, and multifocality in predicting central and massive lymph node metastasis. Additionally, the evaluation of preoperative markers such as calcitonin and carcinoembryonic antigen in synchronous carcinomas is crucial. The relationship between body mass index and the aggressiveness of papillary thyroid carcinoma in males underscores the need for risk stratification based on the former. Metabolomics emerged as a promising tool for identifying non-invasive biomarkers, avoiding unnecessary surgeries. In conclusion, the review underscores the need for a detailed and personalized evaluation of risk factors in the management of papillary thyroid carcinoma. Early identification of biomarkers and the implementation of individualized treatment strategies can significantly improve patient prognosis and quality of life, laying the groundwork for future studies and more precise clinical approaches.

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Published

2024-12-05

How to Cite

1.
Silva Mata MA, Guillén Miranda LE, Lara Jácome AG. Papillary thyroid carcinoma. Rev Cubana Inv Bioméd [Internet]. 2024 Dec. 5 [cited 2025 Jul. 26];43. Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/3598