Association of coronary heart disease with age, sex and genes

Authors

  • María Gabriela Balarezo García
  • Anahí Bonilla Rodríguez
  • Elsy Labrada González

Keywords:

Coronary heart disease, age, sex, genes, Coronary artery disease

Abstract

Introduction: Coronary Heart Disease is the narrowing of the blood vessels that supply blood and oxygen to the heart.

Objective: To associate coronary heart disease with age, sex and genes in patients of a hospital in the city of Tulcán, Ecuador.

Methods: The study was relational, retrospective, observational, analytical and cross-sectional. The sample consisted of 116 patients from a hospital in Tulcán, Ecuador. Simple random sampling was used. The Chi-square test of independence was used using IBM SPSS Statistics software (v. 27.0).

Results: In male patients, Coronary Heart Disease was present in a greater number of cases (75.8 %) compared to female patients, where it was less frequent (24.2 %). Among patients with Coronary Heart Disease, a higher prevalence of associated genes was observed (72.6 %) in contrast to those without these genes (27.4 %). In addition, it was found that, among patients with the disease, there was a higher proportion of smokers (83.9 %) compared with nonsmokers (16.1 %). Statistical tests (Pearson's Chi-square, continuity correction, likelihood ratio and linear by linear association) showed a highly significant value of p < 0.001 in all associations evaluated.

Conclusions: Hypothesis H1 is accepted and hypothesis H0 is rejected, so it is interpreted that there is a significant association between CCT and the variables sex, smoking and genes.

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Published

2024-04-02

How to Cite

1.
Balarezo García MG, Bonilla Rodríguez A, Labrada González E. Association of coronary heart disease with age, sex and genes. Rev Cubana Inv Bioméd [Internet]. 2024 Apr. 2 [cited 2026 Feb. 11];43. Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/3254