Analysis of differences in blood oxygenation in patients with COVID-19 in Ecuador after differentiated treatments

Authors

  • Carlos Troya Altamirano
  • Jenny Maribel Moya Arizaga
  • María Augusta Reyes Pérez

Keywords:

blood oxygenation, hyperbaric oxygen therapy, Remdesivir, COVID-19, Wilcoxon test

Abstract

Introduction: Given the magnitude of COVID-19, it is essential to better understand the therapeutic options and their efficacy.

Objective: The aim of the study was to analyze significant differences in blood oxygenation values in patients admitted to hospitals in Ecuador, diagnosed with COVID-19, after initial treatment with Remdesivir and subsequent treatment with Hyperbaric Oxygen Therapy.

Methods: The study was relational, longitudinal, prospective, observational and analytical. The population consisted of 268 patients with COVID-19. The Wilcoxon signed-rank test was used.

Results: The Difference variable did notó follow a normal distribution (p-value <0.01 in the Kolmogorov-Smirnov test), which supported the choice of the nonparametric Wilcoxon signed-rank test (Z-statistic of -13.467 with a p-value <0.01). The majority of patients (238 cases) experienced an increase in blood oxygen levels after treatment with Hyperbaric Oxygenation Therapy compared to previas levels. The results indicated that, in most cases, blood oxygen levels improved after the application of this treatment. This improvement was supported va Wilcoxon test analysis, which revelad a statistically significant difference between blood oxygen levels before and after the second treatment.

Conclusions: In conclusion, this study provided strong evidence that Hyperbaric Oxygenation Therapy had a significant impact on blood oxygenation in patients with COVID-19 in Ecuador.

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Published

2023-11-08

How to Cite

1.
Troya Altamirano C, Moya Arizaga JM, Reyes Pérez MA. Analysis of differences in blood oxygenation in patients with COVID-19 in Ecuador after differentiated treatments. Rev Cubana Inv Bioméd [Internet]. 2023 Nov. 8 [cited 2025 Jul. 12];42(2). Available from: https://revibiomedica.sld.cu/index.php/ibi/article/view/3062