Diagnóstico neuroinmunológico de meningoencefalitis eosinofílica producida por Angiostrongylus cantonensis

Autores/as

  • Alejandro Ramos Robledo Latoratorio Central de Lìquido Cefalorraquídeo (LABCEL) Facultad de Ciencias Médicas Miguel Enriquez, Universidad de Ciencias Médicas de la HAbana
  • Alberto Juan Dorta Contreras https://orcid.org/0000-0002-8818-4697

Palabras clave:

eosinophilic meningoencephalitis, Angiostrongylus cantonensis, cerebrospinal fluid, diagnosis, IgA, IgG, IgG1, IgG2, C3c, C4, MBL

Resumen

The diagnosis of angiostrongylus cantonensis meningoencephalitis is established by the presence of the helminth larvae in the cerebrospinal fluid, but this evidence is very difficult to find since the larvae are labile in this medium and are not frequently found. Because in Cuba, the presence of the parasite dates back to 1981 and this parasite is the only one that can cause this disease in the country, a review is carried out with the aim of reviewing the literature published on the subject to collect all the evidence that help the auxiliary diagnosis of eosinophilic meningoencephalitis. It is proposed that the study of the intrathecal synthesis of IgE and C3c, together with the pattern of local synthesis of IgA + IgG mainly and IgG1 + IgG2, are the most indicated. There are other proteins that could help as the intrathecal synthesis of C4 and to a lesser extent MBL.

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Publicado

2019-10-03

Cómo citar

1.
Ramos Robledo A, Dorta Contreras AJ. Diagnóstico neuroinmunológico de meningoencefalitis eosinofílica producida por Angiostrongylus cantonensis. Rev Cubana Inv Bioméd [Internet]. 3 de octubre de 2019 [citado 11 de julio de 2025];38(4). Disponible en: https://revibiomedica.sld.cu/index.php/ibi/article/view/e302

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